Pseudomonas fluorescens Pf0-1, Pfl01_4666 (gcbC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas fluorescens Pf0-1
GCF_000012445.1|latest
Locus Tag
Pfl01_4666
Name
gcbC
Replicon chromosome
Genomic location 5266733 - 5268238 (+ strand)

Cross-References

RefSeq YP_350394.1
GI 77460887
Entrez 3714384
INSDC ABA76403.1
NCBI Locus Tag Pfl01_4666
UniParc UPI00003885D8
UniProtKB Acc Q3K751
UniProtKB ID Q3K751_PSEPF
UniRef100 UniRef100_Q3K751
UniRef50 UniRef50_K9NRB3
UniRef90 UniRef90_Q3K751

Product

Feature Type CDS
Coding Frame 1
Product Name
GcbC
Product Name Confidence: Class 1
Synonyms diguanylate cyclase
Evidence for Translation
Charge (pH 7) -1.70
Kyte-Doolittle Hydrophobicity Value -0.055
Molecular Weight (kDa) 55295.2
Isoelectric Point (pI) 6.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5EUH MEMBRANE PROTEIN 11/18/15 Crystal structure of the c-di-GMP-bound GGDEF domain of P. fluorescens GcbC PSEUDOMONAS FLUORESCENS (STRAIN PF0-1) 2.989 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG015202 (196 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Pfl01_4666
Search term: gcbC
Search term: GcbC

Human Homologs

References

Systematic analysis of diguanylate cyclases that promote biofilm formation by Pseudomonas fluorescens Pf0-1.
Newell PD, Yoshioka S, Hvorecny KL, Monds RD, O'Toole GA
J. Bacteriol. 2011 Sep;193(18):4685-98
PubMed ID: 21764921