Pseudomonas putida GB-1, PputGB1_3638

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas putida GB-1
GCF_000019125.1|latest
Locus Tag
PputGB1_3638
Name
Replicon chromosome
Genomic location 4040945 - 4042384 (+ strand)

Cross-References

RefSeq YP_001669865.1
GI 167034634
EC Number 3.5.2.2
Entrez 5871430
INSDC ABY99529.1
NCBI Locus Tag PputGB1_3638
UniParc UPI0000F24600
UniProtKB Acc B0KMS5
UniProtKB ID B0KMS5_PSEPG
UniRef100 UniRef100_B0KMS5
UniRef50 UniRef50_Q59699
UniRef90 UniRef90_Q9I676

Product

Feature Type CDS
Coding Frame 1
Product Name
phenylhydantoinase
Synonyms
Evidence for Translation
Charge (pH 7) -12.60
Kyte-Doolittle Hydrophobicity Value -0.246
Molecular Weight (kDa) 52481.7
Isoelectric Point (pI) 5.77

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6AJD HYDROLASE 08/27/18 Crystal structure of a monometallic dihydropyrimidinase from Pseudomonas aeruginosa PAO1 reveals no lysine carbamylation within the active site Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.223 X-RAY DIFFRACTION 92.0
5YKD HYDROLASE 10/14/17 Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1 at 2.17 angstrom resolution Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.17 X-RAY DIFFRACTION 91.9
5E5C HYDROLASE 10/08/15 Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) 2.1 X-RAY DIFFRACTION 92.0
7E3U HYDROLASE 02/09/21 Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-AU Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.159 X-RAY DIFFRACTION 91.9
6KLK HYDROLASE 07/30/19 Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-FU Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.759 X-RAY DIFFRACTION 91.9

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 560 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000432 (819 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PputGB1_3638

Human Homologs

Ensembl 110, assembly GRCh38.p14
dihydropyrimidinase [Source:HGNC Symbol;Acc:HGNC:3013]
E-value: 3.2e-141
Percent Identity: 52.1

References

No references are associated with this feature.