Pseudomonas putida GB-1, PputGB1_3992

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas putida GB-1
GCF_000019125.1|latest
Locus Tag
PputGB1_3992
Name
Replicon chromosome
Genomic location 4440426 - 4442387 (- strand)

Cross-References

RefSeq YP_001670218.1
GI 167034987
Entrez 5871792
NCBI Locus Tag PputGB1_3992

Product

Feature Type CDS
Coding Frame 1
Product Name
acetyl-CoA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -7.41
Kyte-Doolittle Hydrophobicity Value -0.190
Molecular Weight (kDa) 71854.2
Isoelectric Point (pI) 6.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
Coenzyme A DB01992 DrugBank 5.1.4 Q8ZKF6 Acetyl-coenzyme A synthetase 68.4 652 6.3e-276
Adenosine-5'-Propylphosphate DB03230 DrugBank 5.1.4 Q8ZKF6 Acetyl-coenzyme A synthetase 68.4 652 6.3e-276

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 585 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000854 (1000 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PputGB1_3992

Human Homologs

Ensembl 110, assembly GRCh38.p14
acyl-CoA synthetase short chain family member 2 [Source:HGNC Symbol;Acc:HGNC:15814]
E-value: 2.6e-202
Percent Identity: 53.2

References

No references are associated with this feature.