Pseudomonas putida HB3267, B479_17135

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas putida HB3267
GCF_000325725.1|latest
Locus Tag
B479_17135
Name
Replicon chromosome
Genomic location 3753349 - 3754788 (+ strand)

Cross-References

RefSeq YP_007230262.1
GI 431803359
EC Number 3.5.2.-
Entrez 14289810
INSDC AGA74319.1
NCBI Locus Tag B479_17135
UniParc UPI00021740C1
UniProtKB Acc L0FK19
UniProtKB ID L0FK19_PSEPU
UniRef100 UniRef100_A0A099N182
UniRef50 UniRef50_Q59699
UniRef90 UniRef90_Q9I676

Product

Feature Type CDS
Coding Frame 1
Product Name
phenylhydantoinase
Synonyms
Evidence for Translation
Charge (pH 7) -8.60
Kyte-Doolittle Hydrophobicity Value -0.239
Molecular Weight (kDa) 52.4
Isoelectric Point (pI) 6.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6AJD HYDROLASE 08/27/18 Crystal structure of a monometallic dihydropyrimidinase from Pseudomonas aeruginosa PAO1 reveals no lysine carbamylation within the active site PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.223 X-RAY DIFFRACTION 92.2
6KLK HYDROLASE 07/30/19 Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-FU PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.759 X-RAY DIFFRACTION 92.1
5E5C HYDROLASE 10/08/15 Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1 PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) 2.1 X-RAY DIFFRACTION 92.2
5YKD HYDROLASE 10/14/17 Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1 at 2.17 angstrom resolution PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.17 X-RAY DIFFRACTION 92.1

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 561 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000432 (845 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: B479_17135

Human Homologs

Ensembl 97, assembly GRCh38.p12
dihydropyrimidinase [Source:HGNC Symbol;Acc:HGNC:3013]
E-value: 9.6e-142
Percent Identity: 52.5

References

No references are associated with this feature.