Pseudomonas syringae pv. syringae B728a, Psyr_2728

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas syringae pv. syringae B728a (Feil et al., 2005)
GCF_000012245.1|latest
Locus Tag
Psyr_2728
Name
Replicon chromosome
Genomic location 3311551 - 3312381 (- strand)

Cross-References

RefSeq YP_235805.1
GI 66045964
EC Number 4.2.1.17
Entrez 3368245
INSDC AAY37767.1
NCBI Locus Tag Psyr_2728
UniParc UPI0000394BA4
UniProtKB Acc Q4ZSV5
UniProtKB ID Q4ZSV5_PSEU2
UniRef100 UniRef100_Q4ZSV5
UniRef50 UniRef50_O69762
UniRef90 UniRef90_O69762

Product

Feature Type CDS
Coding Frame 1
Product Name
p-hydroxycinnamoyl CoA hydratase/lyase
Synonyms
Evidence for Translation
Charge (pH 7) -2.63
Kyte-Doolittle Hydrophobicity Value -0.384
Molecular Weight (kDa) 31119.5
Isoelectric Point (pI) 5.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6L3P LYASE 10/14/19 Crystal strcuture of Feruloyl-CoA hydratase lyase(FCHL) complexed with CoA Pseudomonas putida KT2440 2.5 X-RAY DIFFRACTION 90.9
2J5I LYASE 09/18/06 Crystal Structure of Hydroxycinnamoyl-CoA Hydratase-Lyase PSEUDOMONAS FLUORESCENS 1.8 X-RAY DIFFRACTION 94.9
2VSU LYASE 04/29/08 A ternary complex of Hydroxycinnamoyl-CoA Hydratase-Lyase (HCHL) with acetyl-Coenzyme A and vanillin gives insights into substrate specificity and mechanism. PSEUDOMONAS FLUORESCENS 1.9 X-RAY DIFFRACTION 94.6
2VSS LYASE 04/29/08 Wild-type Hydroxycinnamoyl-CoA hydratase lyase in complex with acetyl- CoA and vanillin PSEUDOMONAS FLUORESCENS 2.22 X-RAY DIFFRACTION 94.9

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 494 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG016253 (84 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Psyr_2728

Human Homologs

References

No references are associated with this feature.