Pseudomonas aeruginosa UCBPP-PA14, PA14_00380 (betC)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_00380
Name	betC
Replicon	chromosome
Genomic location	33021 - 34532 (- strand)
Transposon Mutants	2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	YP_788186.1
GI	116053751
Entrez	4384749
INSDC	ABJ14987.1
NCBI Locus Tag	PA14_00380
UniParc	UPI000045D36B
UniProtKB Acc	Q02V50
UniProtKB ID	Q02V50_PSEAB
UniRef100	UniRef100_Q02V50
UniRef50	UniRef50_Q4KKQ0
UniRef90	UniRef90_A6UX93

Product

Feature Type	CDS
Coding Frame	1
Product Name	choline sulfatase
Synonyms
Evidence for Translation
Charge (pH 7)	-6.66
Kyte-Doolittle Hydrophobicity Value	-0.430
Molecular Weight (kDa)	57.4
Isoelectric Point (pI)	6.38

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 272 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000031 (496 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_00380 Search term: betC Search term: choline sulfatase

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000339801 iduronate 2-sulfatase [Source:HGNC Symbol;Acc:HGNC:5389] E-value: 2.6e-32 Percent Identity: 28.7

References