Pseudomonas aeruginosa UCBPP-PA14, PA14_01620 (aptA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_01620
Name
aptA
Replicon chromosome
Genomic location 147341 - 148687 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq YP_788290.1
GI 116053853
EC Number 2.6.1.18
Entrez 4384249
INSDC ABJ15089.1
NCBI Locus Tag PA14_01620
UniParc UPI000045D393
UniProtKB Acc Q02UU6
UniProtKB ID Q02UU6_PSEAB
UniRef100 UniRef100_Q02UU6
UniRef50 UniRef50_Q9I700
UniRef90 UniRef90_Q9I700

Product

Feature Type CDS
Coding Frame 1
Product Name
beta alanine--pyruvate transaminase
Synonyms
Evidence for Translation
Charge (pH 7) -3.78
Kyte-Doolittle Hydrophobicity Value -0.088
Molecular Weight (kDa) 48.4
Isoelectric Point (pI) 6.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4BQ0 TRANSFERASE 05/29/13 Pseudomonas aeruginosa beta-alanine:pyruvate aminotransferase holoenzyme without divalent cations on dimer-dimer interface PSEUDOMONAS AERUGINOSA 1.77 X-RAY DIFFRACTION 99.8
4B98 TRANSFERASE 09/03/12 The structure of the omega aminotransferase from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 1.65 X-RAY DIFFRACTION 99.8
4B9B TRANSFERASE 09/03/12 The structure of the omega aminotransferase from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 1.64 X-RAY DIFFRACTION 99.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 638 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000130 (850 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_01620
Search term: aptA

Human Homologs

Ensembl 110, assembly GRCh38.p14
ornithine aminotransferase [Source:HGNC Symbol;Acc:HGNC:8091]
E-value: 6.5e-35
Percent Identity: 27.0

References

No references are associated with this feature.