Pseudomonas aeruginosa UCBPP-PA14, PA14_02220

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_02220
Name
Replicon	chromosome
Genomic location	198460 - 200499 (- strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	6 transposon mutants in orthologs

Cross-References

RefSeq	YP_788334.1
GI	116053897
Entrez	4383576
INSDC	ABJ15133.1
NCBI Locus Tag	PA14_02220
UniParc	UPI000045D3A4
UniProtKB Acc	Q02UQ2
UniProtKB ID	Q02UQ2_PSEAB
UniRef100	UniRef100_S0I327
UniRef50	UniRef50_Q9I6V6
UniRef90	UniRef90_Q9I6V6

Product

Feature Type	CDS
Coding Frame	1
Product Name	chemotaxis transducer
Synonyms
Evidence for Translation
Charge (pH 7)	-18.01
Kyte-Doolittle Hydrophobicity Value	-0.244
Molecular Weight (kDa)	72.6
Isoelectric Point (pI)	4.84

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
4I3M	SIGNALING PROTEIN	11/26/12	Aer2 poly-HAMP domains: L44H HAMP1 CW-lock mutant	Pseudomonas aeruginosa	1.95	X-RAY DIFFRACTION	99.4
4HI4	SIGNALING PROTEIN	10/11/12	Crystal structure of the 5-coordinate ferric heme-binding PAS domain of Aer2 from P. aeruginosa	Pseudomonas aeruginosa	2.304	X-RAY DIFFRACTION	95.0
3VOL	SIGNALING PROTEIN	01/27/12	X-ray Crystal Structure of PAS-HAMP Aer2 in the CN-bound Form	Pseudomonas aeruginosa	2.399	X-RAY DIFFRACTION	97.2
3LNR	SIGNALING PROTEIN	02/02/10	Crystal structure of poly-HAMP domains from the P. aeruginosa soluble receptor Aer2	Pseudomonas aeruginosa	2.64	X-RAY DIFFRACTION	100.0
4I44	SIGNALING PROTEIN	11/27/12	Aer2 poly-HAMP domains: V33G HAMP1 inverted signaling mutant	Pseudomonas aeruginosa	2.88	X-RAY DIFFRACTION	99.4

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 398 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000174 (385 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_02220 Search term: chemotaxis transducer

Human Homologs

References