Pseudomonas aeruginosa UCBPP-PA14, PA14_05770 (dhT)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
GCF_000014625.1|latest
Locus Tag
PA14_05770
Name
dhT
Replicon chromosome
Genomic location 509567 - 511006 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 14 transposon mutants in orthologs

Cross-References

RefSeq YP_788615.1
GI 116054172
EC Number 3.5.2.2
Entrez 4384309
INSDC ABJ15408.1
NCBI Locus Tag PA14_05770
UniParc UPI00000C5058
UniProtKB Acc Q02TX1
UniProtKB ID Q02TX1_PSEAB
UniRef100 UniRef100_Q9I676
UniRef50 UniRef50_Q59699
UniRef90 UniRef90_Q9I676

Product

Feature Type CDS
Coding Frame 1
Product Name
phenylhydantoinase
Synonyms
Evidence for Translation
Charge (pH 7) -9.36
Kyte-Doolittle Hydrophobicity Value -0.171
Molecular Weight (kDa) 52.2
Isoelectric Point (pI) 6.17

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6AJD HYDROLASE 08/27/18 Crystal structure of a monometallic dihydropyrimidinase from Pseudomonas aeruginosa PAO1 reveals no lysine carbamylation within the active site PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.223 X-RAY DIFFRACTION 100.0
5YKD HYDROLASE 10/14/17 Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1 at 2.17 angstrom resolution PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.17 X-RAY DIFFRACTION 100.0
6KLK HYDROLASE 07/30/19 Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-FU PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.759 X-RAY DIFFRACTION 100.0
5E5C HYDROLASE 10/08/15 Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1 PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) 2.1 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 561 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000432 (845 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_05770
Search term: dhT

Human Homologs

Ensembl 97, assembly GRCh38.p12
dihydropyrimidinase [Source:HGNC Symbol;Acc:HGNC:3013]
E-value: 8.4e-138
Percent Identity: 51.2

References

No references are associated with this feature.