Pseudomonas aeruginosa UCBPP-PA14, PA14_25110 (topA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_25110
Name
topA
Replicon chromosome
Genomic location 2196651 - 2199257 (+ strand)
Transposon Mutants 3 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq YP_790161.1
GI 116051012
EC Number 5.99.1.2
Entrez 4384430
INSDC ABJ12248.1
NCBI Locus Tag PA14_25110
UniParc UPI0000137145
UniProtKB Acc Q02PH5
UniProtKB ID Q02PH5_PSEAB
UniRef100 UniRef100_Q9HZJ5
UniRef50 UniRef50_Q9HZJ5
UniRef90 UniRef90_Q9HZJ5

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA topoisomerase I
Synonyms
Evidence for Translation
Charge (pH 7) 13.98
Kyte-Doolittle Hydrophobicity Value -0.617
Molecular Weight (kDa) 97.3
Isoelectric Point (pI) 8.66

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 665 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002571 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_25110
Search term: topA

Human Homologs

References

No references are associated with this feature.