Pseudomonas aeruginosa UCBPP-PA14, PA14_41570 (oprF)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_41570
Name	oprF
Replicon	chromosome
Genomic location	3712447 - 3713499 (- strand)
Transposon Mutants	2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	YP_791468.1
GI	116049726
Entrez	4382883
INSDC	ABJ10962.1
NCBI Locus Tag	PA14_41570
UniParc	UPI000002B99B
UniProtKB Acc	Q02KR8
UniProtKB ID	Q02KR8_PSEAB
UniRef100	UniRef100_P13794
UniRef50	UniRef50_P13794
UniRef90	UniRef90_P13794

Product

Feature Type	CDS
Coding Frame	1
Product Name	major porin and structural outer membrane porin OprF precursor
Synonyms
Evidence for Translation
Charge (pH 7)	-11.67
Kyte-Doolittle Hydrophobicity Value	-0.443
Molecular Weight (kDa)	37.6
Isoelectric Point (pI)	4.75

Subcellular localization

Individual Mappings	Localization Confidence PMID Outer Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
4RLC	TRANSPORT PROTEIN	10/16/14	Crystal structure of the N-terminal beta-barrel domain of Pseudomonas aeruginosa OprF	Pseudomonas aeruginosa	1.6	X-RAY DIFFRACTION	100.0
5U1H	PEPTIDE BINDING PROTEIN	11/28/16	Crystal structure of the C-terminal peptidoglycan binding domain of OprF (PA1777) from Pseudomonas aeruginosa	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	1.5	X-RAY DIFFRACTION	100.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 441 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003618 (537 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_41570 Search term: oprF Search term: major porin and structural outer membrane porin OprF precursor

Human Homologs

References