Pseudomonas aeruginosa UCBPP-PA14, PA14_49470 (nrdB)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_49470
Name	nrdB
Replicon	chromosome
Genomic location	4397858 - 4399105 (+ strand)

Cross-References

RefSeq	YP_792111.1
GI	116049087
EC Number	1.17.4.1
Entrez	4381685
INSDC	ABJ10323.1
NCBI Locus Tag	PA14_49470
UniParc	UPI00000C5279
UniProtKB Acc	Q02IX5
UniProtKB ID	Q02IX5_PSEAB
UniRef100	UniRef100_Q9I4I2
UniRef50	UniRef50_Q9I4I2
UniRef90	UniRef90_Q9I4I2

Product

Feature Type	CDS
Coding Frame	1
Product Name	ribonucleotide-diphosphate reductase subunit beta
Synonyms
Evidence for Translation
Charge (pH 7)	-21.44
Kyte-Doolittle Hydrophobicity Value	-0.431
Molecular Weight (kDa)	47.4
Isoelectric Point (pI)	4.50

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 403 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001114 (536 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_49470 Search term: nrdB Search term: ribonucleotide-diphosphate reductase subunit beta

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000428115 ribonucleotide reductase regulatory TP53 inducible subunit M2B [Source:HGNC Symbol;Acc:HGNC:17296] E-value: 7.9e-35 Percent Identity: 26.5

References