Pseudomonas aeruginosa UCBPP-PA14, PA14_50700 (shaC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_50700
Name
shaC
Replicon chromosome
Genomic location 4502712 - 4503236 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq YP_792212.1
GI 116048986
Entrez 4384766
INSDC ABJ10222.1
NCBI Locus Tag PA14_50700
UniParc UPI0000E44B65
UniProtKB Acc Q02IM4
UniProtKB ID Q02IM4_PSEAB
UniRef100 UniRef100_Q02IM4
UniRef50 UniRef50_Q02IM4
UniRef90 UniRef90_Q02IM4

Product

Feature Type CDS
Coding Frame 1
Product Name
ShaC
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 0.89
Kyte-Doolittle Hydrophobicity Value 0.751
Molecular Weight (kDa) 19.3
Isoelectric Point (pI) 7.58

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 212 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001019 (421 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_50700
Search term: shaC
Search term: ShaC

Human Homologs

References

Characterization of a multigene-encoded sodium/hydrogen antiporter (sha) from Pseudomonas aeruginosa: its involvement in pathogenesis.
Kosono S, Haga K, Tomizawa R, Kajiyama Y, Hatano K, Takeda S, Wakai Y, Hino M, Kudo T
J Bacteriol 2005 Aug;187(15):5242-8
PubMed ID: 16030218