Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
Locus Tag |
PA14_71990
|
Name |
gmd
|
Replicon | chromosome |
Genomic location | 6416029 - 6417000 (- strand) |
Transposon Mutants | 1 transposon mutants in UCBPP-PA14 |
Transposon Mutants in orthologs | 5 transposon mutants in orthologs |
RefSeq | YP_793930.1 |
GI | 116053603 |
Entrez | 4384948 |
INSDC | ABJ14839.1 |
NCBI Locus Tag | PA14_71990 |
UniParc | UPI000012B8A1 |
UniProtKB Acc | Q02DQ6 |
UniProtKB ID | Q02DQ6_PSEAB |
UniRef100 | UniRef100_Q51366 |
UniRef50 | UniRef50_Q51366 |
UniRef90 | UniRef90_Q51366 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
GDP-mannose 4,6-dehydratase
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -1.61 |
Kyte-Doolittle Hydrophobicity Value | -0.291 |
Molecular Weight (kDa) | 36.4 |
Isoelectric Point (pI) | 6.53 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
1RPN | LYASE | 12/03/03 | Crystal Structure of GDP-D-mannose 4,6-dehydratase in complexes with GDP and NADPH | Pseudomonas aeruginosa | 2.15 | X-RAY DIFFRACTION | 100.0 |
Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.
Drug Name | Source Accession | Source DB | Version | Target Accession | Target Description | Percent Identity | Alignment Length | E-Value |
Guanosine-5'-Diphosphate | DB04315 | DrugBank | 5.1.4 | Q51366 | GDP-mannose 4,6-dehydratase | 100.0 | 323 | 1.3e-186 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 611 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004999 (381 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_71990
Search term: gmd
Search term: GDP-mannose 4,6-dehydratase
|
Ensembl
110, assembly
GRCh38.p14
|
GDP-mannose 4,6-dehydratase [Source:HGNC Symbol;Acc:HGNC:4369]
E-value:
3.1e-87
Percent Identity:
48.2
|