Pseudomonas aeruginosa PA7, PSPA7_2146 (fadA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_2146
Name
fadA
Replicon chromosome
Genomic location 2200843 - 2202018 (+ strand)

Cross-References

RefSeq YP_001347518.1
GI 152983511
EC Number 2.3.1.16
Entrez 5359206
INSDC ABR80694.1
NCBI Locus Tag PSPA7_2146
UniParc UPI0000395F77
UniProtKB Acc A6V383
UniProtKB ID FADA_PSEA7
UniRef100 UniRef100_A6V383
UniRef50 UniRef50_P21151
UniRef90 UniRef90_P28790

Product

Feature Type CDS
Coding Frame 1
Product Name
3-ketoacyl-CoA thiolase
Synonyms
Evidence for Translation
Charge (pH 7) -0.26
Kyte-Doolittle Hydrophobicity Value -0.050
Molecular Weight (kDa) 41.6
Isoelectric Point (pI) 6.95

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1WDK LYASE,OXIDOREDUCTASE/TRANSFERASE 05/17/04 fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native2) Pseudomonas fragi 2.5 X-RAY DIFFRACTION 90.8
2D3T LYASE, OXIDOREDUCTASE/TRANSFERASE 10/01/05 Fatty Acid beta-oxidation multienzyme complex from Pseudomonas Fragi, Form V Pseudomonas fragi 3.4 X-RAY DIFFRACTION 90.8
1WDL LYASE,OXIDOREDUCTASE/TRANSFERASE 05/17/04 fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form II (native4) Pseudomonas fragi 3.5 X-RAY DIFFRACTION 90.8
1WDM LYASE,OXIDOREDUCTASE/TRANSFERASE 05/17/04 fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native3) Pseudomonas fragi 3.8 X-RAY DIFFRACTION 90.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 477 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002569 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_2146
Search term: fadA

Human Homologs

Ensembl 110, assembly GRCh38.p14
acetyl-CoA acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:82]
E-value: 3.2e-62
Percent Identity: 40.4

References

No references are associated with this feature.