Pseudomonas aeruginosa PA7, PSPA7_2148 (topA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PA7
GCF_000017205.1|latest |
| Locus Tag |
PSPA7_2148
|
| Name |
topA
|
| Replicon | chromosome |
| Genomic location | 2202565 - 2205171 (+ strand) |
Cross-References
| RefSeq | YP_001347520.1 |
| GI | 152987110 |
| EC Number | 5.99.1.2 |
| Entrez | 5358167 |
| NCBI Locus Tag | PSPA7_2148 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
DNA topoisomerase I
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 13.98 |
| Kyte-Doolittle Hydrophobicity Value | -0.611 |
| Molecular Weight (kDa) | 97252.9 |
| Isoelectric Point (pI) | 8.66 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 665 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG002571 (536 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PSPA7_2148
Search term: topA
Search term: DNA topoisomerase I
|
Human Homologs
References
No references are associated with this feature.