Pseudomonas aeruginosa PA7, PSPA7_2596 (serS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_2596
Name
serS
Replicon chromosome
Genomic location 2619449 - 2620729 (+ strand)

Cross-References

RefSeq YP_001347960.1
GI 152989408
EC Number 6.1.1.11
Entrez 5353919
INSDC ABR86591.1
NCBI Locus Tag PSPA7_2596
UniParc UPI0000D73165
UniProtKB Acc A6V4H5
UniProtKB ID SYS_PSEA7
UniRef100 UniRef100_A6V4H5
UniRef50 UniRef50_Q6F8G5
UniRef90 UniRef90_A4VLU7

Product

Feature Type CDS
Coding Frame 1
Product Name
seryl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -9.93
Kyte-Doolittle Hydrophobicity Value -0.362
Molecular Weight (kDa) 47.3
Isoelectric Point (pI) 5.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6HE1 LIGASE 08/20/18 Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine Pseudomonas aeruginosa 2.22 X-RAY DIFFRACTION 98.6
6HE3 LIGASE 08/20/18 Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)cytidine Pseudomonas aeruginosa 2.16 X-RAY DIFFRACTION 98.6
6HDZ LIGASE 08/20/18 Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-Sulfamoyl)uridine Pseudomonas aeruginosa 2.06 X-RAY DIFFRACTION 98.6

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 651 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002939 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_2596
Search term: serS

Human Homologs

Ensembl 110, assembly GRCh38.p14
seryl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:10537]
E-value: 3.9e-53
Percent Identity: 36.3

References

No references are associated with this feature.