Pseudomonas aeruginosa PA7, PSPA7_2744 (mexF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_2744
Name
mexF
Replicon chromosome
Genomic location 2766375 - 2769563 (- strand)

Cross-References

RefSeq YP_001348104.1
GI 152988263
Entrez 5358765
NCBI Locus Tag PSPA7_2744

Product

Feature Type CDS
Coding Frame 1
Product Name
RND multidrug efflux transporter MexF
Synonyms
Evidence for Translation
Charge (pH 7) -10.67
Kyte-Doolittle Hydrophobicity Value 0.289
Molecular Weight (kDa) 115.4
Isoelectric Point (pI) 5.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
adeF AdeF is the membrane fusion protein of the multidrug efflux complex AdeFGH. [PMID:20696879] ARO:3000777 protein homolog model Strict 1337.8 67.4 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 488 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000417 (2093 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_2744
Search term: mexF

Human Homologs

References

No references are associated with this feature.