Pseudomonas aeruginosa PA7, PSPA7_2745 (mexE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_2745
Name
mexE
Replicon chromosome
Genomic location 2769585 - 2770829 (- strand)

Cross-References

RefSeq YP_001348105.1
GI 152984257
Entrez 5354865
NCBI Locus Tag PSPA7_2745

Product

Feature Type CDS
Coding Frame 1
Product Name
RND multidrug efflux membrane fusion protein MexE
Synonyms
Evidence for Translation
Charge (pH 7) 2.71
Kyte-Doolittle Hydrophobicity Value -0.349
Molecular Weight (kDa) 45148.7
Isoelectric Point (pI) 8.84

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
MexE MexE is the membrane fusion protein of the MexEF-OprN multidrug efflux complex. [PMID:10515918] ARO:3000803 protein homolog model Strict 779.2 98.79 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 414 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003063 (526 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_2745
Search term: mexE

Human Homologs

References

No references are associated with this feature.