Pseudomonas aeruginosa PA7, PSPA7_4387 (dapA)

Cytoplasmic Membrane
Outer Membrane
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
Locus Tag
Replicon chromosome
Genomic location 4517214 - 4518092 (- strand)


RefSeq YP_001349739.1
GI 152984603
EC Number
Entrez 5355827
NCBI Locus Tag PSPA7_4387


Feature Type CDS
Coding Frame 1
Product Name
dihydrodipicolinate synthase
Evidence for Translation
Charge (pH 7) -2.44
Kyte-Doolittle Hydrophobicity Value 0.041
Molecular Weight (kDa) 31.5
Isoelectric Point (pI) 6.40

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3S8H LYASE 05/28/11 Structure of dihydrodipicolinate synthase complexed with 3-Hydroxypropanoic acid(HPA)at 2.70 A resolution Pseudomonas aeruginosa 2.7 X-RAY DIFFRACTION 98.3
6P90 STRUCTURAL PROTEIN 06/08/19 Crystal structure of PaDHDPS2-H56Q mutant Pseudomonas aeruginosa 1.9 X-RAY DIFFRACTION 99.3
3NOE LYASE 06/25/10 Crystal Structure of Dihydrodipicolinate synthase from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.95 X-RAY DIFFRACTION 98.3
3QZE LYASE 03/05/11 Crystal Structure of DapA (PA1010) at 1.6 A resolution Pseudomonas aeruginosa 1.59 X-RAY DIFFRACTION 99.7
3PUO LYASE 12/06/10 Crystal structure of dihydrodipicolinate synthase from Pseudomonas aeruginosa(PsDHDPS)complexed with L-lysine at 2.65A resolution Pseudomonas aeruginosa 2.65 X-RAY DIFFRACTION 98.3
3PS7 LYASE 12/01/10 Biochemical studies and crystal structure determination of dihydrodipicolinate synthase from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.85 X-RAY DIFFRACTION 98.3

Pathogen Association Analysis

Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 633 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000973 (536 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_4387
Search term: dapA

Human Homologs


No references are associated with this feature.