Pseudomonas aeruginosa PA7, PSPA7_4723 (prpC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_4723
Name
prpC
Replicon chromosome
Genomic location 4847996 - 4849123 (+ strand)

Cross-References

RefSeq YP_001350065.1
GI 152989602
Entrez 5357774
NCBI Locus Tag PSPA7_4723

Product

Feature Type CDS
Coding Frame 1
Product Name
methylcitrate synthase
Synonyms
Evidence for Translation
Charge (pH 7) -3.47
Kyte-Doolittle Hydrophobicity Value -0.235
Molecular Weight (kDa) 41.7
Isoelectric Point (pI) 6.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6S87 TRANSFERASE 07/08/19 Crystal structure of 2-methylcitrate synthase (PrpC) from Pseudomonas aeruginosa in complex with oxaloacetate. Pseudomonas aeruginosa PAO1 1.65 X-RAY DIFFRACTION 99.5
6S6F TRANSFERASE 07/03/19 Crystal structure of 2-methylcitrate synthase (PrpC) from Pseudomonas aeruginosa in apo form. Pseudomonas aeruginosa PAO1 1.53 X-RAY DIFFRACTION 99.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 551 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000768 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_4723
Search term: prpC

Human Homologs

References

No references are associated with this feature.