Pseudomonas aeruginosa PA7, PSPA7_5725
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PA7
GCF_000017205.1|latest |
| Locus Tag |
PSPA7_5725
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 5898976 - 5899308 (+ strand) |
Cross-References
| RefSeq | YP_001351044.1 |
| GI | 152989417 |
| Entrez | 5353678 |
| NCBI Locus Tag | PSPA7_5725 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
SMR multidrug efflux transporter
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 3.21 |
| Kyte-Doolittle Hydrophobicity Value | 1.441 |
| Molecular Weight (kDa) | 11.5 |
| Isoelectric Point (pI) | 9.86 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AMR gene predictions from CARD database
Identified using the Resistance Gene Identifier (RGI)
| Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
| Pseudomonas aeruginosa emrE | EmrE is a small multidrug transporter that functions as a homodimer and that couples the efflux of small polyaromatic cations from the cell with the import of protons down an electrochemical gradient. Confers resistance to tetraphenylphosphonium, methyl viologen, gentamicin, kanamycin, and neomycin. [PMID:12499164] | ARO:3004038 | protein homolog model | Strict | 185.3 | 95.45 | 3.2.5 |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 301 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG004600 (529 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PSPA7_5725
Search term: SMR multidrug efflux transporter
|
Human Homologs
References
No references are associated with this feature.