Pseudomonas aeruginosa PA7, PSPA7_6209 (fdhA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_6209
Name
fdhA
Replicon chromosome
Genomic location 6415740 - 6416939 (+ strand)

Cross-References

RefSeq YP_001351520.1
GI 152987995
EC Number 1.2.1.46
Entrez 5358951
INSDC ABR85178.1
NCBI Locus Tag PSPA7_6209
UniParc UPI00015778B0
UniProtKB Acc A6VEN5
UniProtKB ID A6VEN5_PSEA7
UniRef100 UniRef100_A6VEN5
UniRef50 UniRef50_Q52078
UniRef90 UniRef90_Q9HTE3

Product

Feature Type CDS
Coding Frame 1
Product Name
glutathione-independent formaldehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -1.85
Kyte-Doolittle Hydrophobicity Value 0.027
Molecular Weight (kDa) 42.0
Isoelectric Point (pI) 6.75

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4JLW OXIDOREDUCTASE 03/13/13 Crystal structure of formaldehyde dehydrogenase from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.7 X-RAY DIFFRACTION 99.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 533 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003315 (1429 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_6209
Search term: fdhA

Human Homologs

Ensembl 110, assembly GRCh38.p14
sorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184]
E-value: 3.2e-17
Percent Identity: 29.1

References

No references are associated with this feature.