Pseudomonas aeruginosa PA7, PSPA7_6243 (gmd)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_6243
Name
gmd
Replicon chromosome
Genomic location 6456994 - 6457965 (- strand)

Cross-References

RefSeq YP_001351554.1
GI 152986106
EC Number 4.2.1.47
Entrez 5356681
INSDC ABR83289.1
NCBI Locus Tag PSPA7_6243
UniParc UPI0000D727D8
UniProtKB Acc A6VER9
UniProtKB ID A6VER9_PSEA7
UniRef100 UniRef100_A6VER9
UniRef50 UniRef50_Q51366
UniRef90 UniRef90_Q51366

Product

Feature Type CDS
Coding Frame 1
Product Name
GDP-mannose 4,6-dehydratase
Synonyms
Evidence for Translation
Charge (pH 7) -3.61
Kyte-Doolittle Hydrophobicity Value -0.329
Molecular Weight (kDa) 36522.1
Isoelectric Point (pI) 6.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1RPN LYASE 12/03/03 Crystal Structure of GDP-D-mannose 4,6-dehydratase in complexes with GDP and NADPH Pseudomonas aeruginosa 2.15 X-RAY DIFFRACTION 97.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 608 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004999 (389 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_6243
Search term: gmd

Human Homologs

Ensembl 107, assembly GRCh38.p13
GDP-mannose 4,6-dehydratase [Source:HGNC Symbol;Acc:HGNC:4369]
E-value: 2.8e-85
Percent Identity: 47.3

References

No references are associated with this feature.