Pseudomonas aeruginosa M18, PAM18_0176 (aer2)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa M18
GCF_000226155.1|latest |
| Locus Tag |
PAM18_0176
|
| Name |
aer2
|
| Replicon | chromosome |
| Genomic location | 198005 - 200044 (- strand) |
Cross-References
| RefSeq | YP_005972767.1 |
| GI | 386056245 |
| Entrez | 12564193 |
| NCBI Locus Tag | PAM18_0176 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
aerotaxis transducer Aer2
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -18.01 |
| Kyte-Doolittle Hydrophobicity Value | -0.257 |
| Molecular Weight (kDa) | 72.6 |
| Isoelectric Point (pI) | 4.84 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 3LNR | SIGNALING PROTEIN | 02/02/10 | Crystal structure of poly-HAMP domains from the P. aeruginosa soluble receptor Aer2 | Pseudomonas aeruginosa | 2.64 | X-RAY DIFFRACTION | 100.0 |
| 4HI4 | SIGNALING PROTEIN | 10/11/12 | Crystal structure of the 5-coordinate ferric heme-binding PAS domain of Aer2 from P. aeruginosa | Pseudomonas aeruginosa | 2.304 | X-RAY DIFFRACTION | 95.8 |
| 4I44 | SIGNALING PROTEIN | 11/27/12 | Aer2 poly-HAMP domains: V33G HAMP1 inverted signaling mutant | Pseudomonas aeruginosa | 2.88 | X-RAY DIFFRACTION | 99.4 |
| 4I3M | SIGNALING PROTEIN | 11/26/12 | Aer2 poly-HAMP domains: L44H HAMP1 CW-lock mutant | Pseudomonas aeruginosa | 1.95 | X-RAY DIFFRACTION | 99.4 |
| 3VOL | SIGNALING PROTEIN | 01/27/12 | X-ray Crystal Structure of PAS-HAMP Aer2 in the CN-bound Form | Pseudomonas aeruginosa | 2.399 | X-RAY DIFFRACTION | 98.6 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 398 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000174 (385 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PAM18_0176
Search term: aer2
Search term: aerotaxis transducer Aer2
|
Human Homologs
References
No references are associated with this feature.