Pseudomonas aeruginosa M18, PAM18_1947 (fadA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa M18
GCF_000226155.1|latest
Locus Tag
PAM18_1947
Name
fadA
Replicon chromosome
Genomic location 2143736 - 2144911 (+ strand)

Cross-References

RefSeq YP_005974535.1
GI 386058013
Entrez 12565989
NCBI Locus Tag PAM18_1947

Product

Feature Type CDS
Coding Frame 1
Product Name
3-ketoacyl-CoA thiolase
Synonyms
Evidence for Translation
Charge (pH 7) -1.26
Kyte-Doolittle Hydrophobicity Value -0.049
Molecular Weight (kDa) 41.6
Isoelectric Point (pI) 6.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1WDK LYASE,OXIDOREDUCTASE/TRANSFERASE 05/17/04 fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native2) Pseudomonas fragi 2.5 X-RAY DIFFRACTION 90.5
2D3T LYASE, OXIDOREDUCTASE/TRANSFERASE 10/01/05 Fatty Acid beta-oxidation multienzyme complex from Pseudomonas Fragi, Form V Pseudomonas fragi 3.4 X-RAY DIFFRACTION 90.5
1WDL LYASE,OXIDOREDUCTASE/TRANSFERASE 05/17/04 fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form II (native4) Pseudomonas fragi 3.5 X-RAY DIFFRACTION 90.5
1WDM LYASE,OXIDOREDUCTASE/TRANSFERASE 05/17/04 fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native3) Pseudomonas fragi 3.8 X-RAY DIFFRACTION 90.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 478 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002569 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PAM18_1947
Search term: fadA

Human Homologs

Ensembl 110, assembly GRCh38.p14
acetyl-CoA acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:82]
E-value: 3.2e-62
Percent Identity: 40.4

References

No references are associated with this feature.