Pseudomonas aeruginosa M18, PAM18_2546 (mexE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa M18
GCF_000226155.1|latest
Locus Tag
PAM18_2546
Name
mexE
Replicon chromosome
Genomic location 2788984 - 2790228 (- strand)

Cross-References

RefSeq YP_005975131.1
GI 386058609
Entrez 12566596
NCBI Locus Tag PAM18_2546

Product

Feature Type CDS
Coding Frame 1
Product Name
Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexE precursor
Synonyms
Evidence for Translation
Charge (pH 7) 2.71
Kyte-Doolittle Hydrophobicity Value -0.350
Molecular Weight (kDa) 45.0
Isoelectric Point (pI) 8.84

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
MexE MexE is the membrane fusion protein of the MexEF-OprN multidrug efflux complex. [PMID:10515918] ARO:3000803 protein homolog model Perfect 785.4 100.0 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 414 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003063 (526 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PAM18_2546
Search term: mexE

Human Homologs

References

No references are associated with this feature.