Pseudomonas aeruginosa DK2, PADK2_00665

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa DK2
GCF_000271365.1|latest
Locus Tag
PADK2_00665
Name
Replicon chromosome
Genomic location 146702 - 148195 (- strand)

Cross-References

RefSeq YP_006480130.1
GI 392981543
Entrez 13171430
NCBI Locus Tag PADK2_00665

Product

Feature Type CDS
Coding Frame 1
Product Name
methylmalonate-semialdehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -7.37
Kyte-Doolittle Hydrophobicity Value -0.014
Molecular Weight (kDa) 53.3
Isoelectric Point (pI) 5.95

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5TJR OXIDOREDUCTASE 10/05/16 X-ray Crystal structure of a methylmalonate semialdehyde dehydrogenase from Pseudomonas sp. AAC Pseudomonas sp. AAC 2.95 X-RAY DIFFRACTION 91.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 599 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000128 (531 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PADK2_00665

Human Homologs

Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 6 family member A1 [Source:HGNC Symbol;Acc:HGNC:7179]
E-value: 2.3e-126
Percent Identity: 45.6

References

No references are associated with this feature.