Pseudomonas aeruginosa DK2, PADK2_00750

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa DK2
GCF_000271365.1|latest
Locus Tag
PADK2_00750
Name
Replicon chromosome
Genomic location 167322 - 168272 (+ strand)

Cross-References

RefSeq YP_006480147.1
GI 392981560
EC Number 3.5.4.4
Entrez 13171447
NCBI Locus Tag PADK2_00750

Product

Feature Type CDS
Coding Frame 1
Product Name
adenosine deaminase
Synonyms
Evidence for Translation
Charge (pH 7) -14.43
Kyte-Doolittle Hydrophobicity Value -0.275
Molecular Weight (kDa) 36.2
Isoelectric Point (pI) 4.87

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3PAN HYDROLASE 10/19/10 The crystal structure of adenosine deaminase with hypoxanthine bound from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.627 X-RAY DIFFRACTION 99.7
3OU8 HYDROLASE 09/14/10 The crystal structure of adenosine deaminase from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.51 X-RAY DIFFRACTION 99.7
3PBM HYDROLASE 10/20/10 The crystal structure of adenosine deaminase in complex with chloropurine from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.591 X-RAY DIFFRACTION 99.7
3PAO HYDROLASE 10/19/10 The crystal structure of adenosine deaminase with adenine bound from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.493 X-RAY DIFFRACTION 99.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 254 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000146 (532 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PADK2_00750

Human Homologs

Ensembl 110, assembly GRCh38.p14
adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186]
E-value: 1.7e-21
Percent Identity: 23.6

References

No references are associated with this feature.