Pseudomonas aeruginosa DK2, PADK2_02150

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa DK2
GCF_000271365.1|latest
Locus Tag
PADK2_02150
Name
Replicon chromosome
Genomic location 467199 - 470156 (+ strand)

Cross-References

RefSeq YP_006480425.1
GI 392981838
Entrez 13171966
NCBI Locus Tag PADK2_02150

Product

Feature Type CDS
Coding Frame 1
Product Name
RND multidrug efflux transporter MexB
Synonyms
Evidence for Translation
Charge (pH 7) -9.89
Kyte-Doolittle Hydrophobicity Value 0.287
Molecular Weight (kDa) 106168.1
Isoelectric Point (pI) 5.38

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6IOK MEMBRANE PROTEIN 10/30/18 Cryo-EM structure of multidrug efflux pump MexAB-OprM (0 degree state) Pseudomonas aeruginosa PAO1 3.64 ELECTRON MICROSCOPY 94.2
2V50 MEMBRANE PROTEIN 10/01/08 The Missing Part of the Bacterial MexAB-OprM System: Structural determination of the Multidrug Exporter MexB PSEUDOMONAS AERUGINOSA PA01 3 X-RAY DIFFRACTION 94.1
6IOL MEMBRANE PROTEIN 10/30/18 Cryo-EM structure of multidrug efflux pump MexAB-OprM (60 degree state) Pseudomonas aeruginosa; Pseudomonas aeruginosa PAO1 3.76 ELECTRON MICROSCOPY 94.2
6IIA MEMBRANE PROTEIN 10/04/18 MexB in complex with LMNG Pseudomonas aeruginosa PAO1 2.91 X-RAY DIFFRACTION 94.1
3W9I MEMBRANE PROTEIN 04/04/13 Structural basis for the inhibition of bacterial multidrug exporters Pseudomonas aeruginosa 2.71 X-RAY DIFFRACTION 94.2
3W9J MEMBRANE PROTEIN 04/04/13 Structural basis for the inhibition of bacterial multidrug exporters Pseudomonas aeruginosa 3.15 X-RAY DIFFRACTION 94.1

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 487 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000417 (2093 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PADK2_02150

Human Homologs

References

No references are associated with this feature.