Pseudomonas aeruginosa DK2, PADK2_05485 (guaA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa DK2
GCF_000271365.1|latest
Locus Tag
PADK2_05485
Name
guaA
Replicon chromosome
Genomic location 1178022 - 1179599 (+ strand)

Cross-References

RefSeq YP_006481092.1
GI 392982505
EC Number 6.3.5.2
Entrez 13172644
NCBI Locus Tag PADK2_05485

Product

Feature Type CDS
Coding Frame 1
Product Name
GMP synthase
Synonyms
Evidence for Translation
Charge (pH 7) -13.83
Kyte-Doolittle Hydrophobicity Value 0.003
Molecular Weight (kDa) 58.0
Isoelectric Point (pI) 5.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 652 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001894 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PADK2_05485
Search term: guaA
Search term: GMP synthase

Human Homologs

Ensembl 110, assembly GRCh38.p14
guanine monophosphate synthase [Source:HGNC Symbol;Acc:HGNC:4378]
E-value: 2.3e-79
Percent Identity: 35.6

References

No references are associated with this feature.