Pseudomonas aeruginosa DK2, PADK2_11600

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa DK2
GCF_000271365.1|latest
Locus Tag
PADK2_11600
Name
Replicon chromosome
Genomic location 2463557 - 2464837 (+ strand)

Cross-References

RefSeq YP_006482305.1
GI 392983718
EC Number 6.1.1.11
Entrez 13174515
NCBI Locus Tag PADK2_11600

Product

Feature Type CDS
Coding Frame 1
Product Name
seryl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -9.93
Kyte-Doolittle Hydrophobicity Value -0.356
Molecular Weight (kDa) 47.2
Isoelectric Point (pI) 5.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6HDZ LIGASE 08/20/18 Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-Sulfamoyl)uridine Pseudomonas aeruginosa 2.06 X-RAY DIFFRACTION 99.8
6HE1 LIGASE 08/20/18 Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine Pseudomonas aeruginosa 2.22 X-RAY DIFFRACTION 99.8
6HE3 LIGASE 08/20/18 Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)cytidine Pseudomonas aeruginosa 2.16 X-RAY DIFFRACTION 99.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 651 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002939 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PADK2_11600

Human Homologs

Ensembl 110, assembly GRCh38.p14
seryl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:10537]
E-value: 1.5e-52
Percent Identity: 32.2

References

No references are associated with this feature.