Pseudomonas aeruginosa DK2, PADK2_12775

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa DK2
GCF_000271365.1|latest
Locus Tag
PADK2_12775
Name
Replicon chromosome
Genomic location 2705000 - 2708188 (- strand)

Cross-References

RefSeq YP_006482538.1
GI 392983951
Entrez 13175392
NCBI Locus Tag PADK2_12775

Product

Feature Type CDS
Coding Frame 1
Product Name
RND multidrug efflux transporter MexF
Synonyms
Evidence for Translation
Charge (pH 7) -11.43
Kyte-Doolittle Hydrophobicity Value 0.284
Molecular Weight (kDa) 115.5
Isoelectric Point (pI) 5.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). [PMID:10515918] ARO:3000804 protein homolog model Perfect 2016.5 100.0 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 488 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000417 (2093 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PADK2_12775

Human Homologs

References

No references are associated with this feature.