Pseudomonas aeruginosa DK2, PADK2_12785

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa DK2
GCF_000271365.1|latest
Locus Tag
PADK2_12785
Name
Replicon chromosome
Genomic location 2709684 - 2710598 (- strand)

Cross-References

RefSeq YP_006482540.1
GI 392983953
Entrez 13175394
NCBI Locus Tag PADK2_12785

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator MexT
Synonyms
Evidence for Translation
Charge (pH 7) 0.70
Kyte-Doolittle Hydrophobicity Value -0.066
Molecular Weight (kDa) 33.4
Isoelectric Point (pI) 7.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
MexT MexT is a LysR-type transcriptional activator that positively regulates the expression of MexEF-OprN, OprD, and MexS. [PMID:11040437, PMID:26833155, PMID:10515918] ARO:3000814 protein overexpression model Strict 524.6 99.63 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6L33 TRANSCRIPTION 10/08/19 Crystal structure of the regulatory domain of MexT, a transcriptional activator in Pseudomonas aeruginosa Pseudomonas aeruginosa 2 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 325 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001179 (1943 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PADK2_12785

Human Homologs

References

No references are associated with this feature.