Pseudomonas aeruginosa B136-33, G655_11940

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa B136-33
GCF_000359505.1|latest
Locus Tag
G655_11940
Name
Replicon chromosome
Genomic location 2555577 - 2556857 (+ strand)

Cross-References

RefSeq YP_007709233.1
GI 478478582
EC Number 6.1.1.11
Entrez 15135298
NCBI Locus Tag G655_11940

Product

Feature Type CDS
Coding Frame 1
Product Name
seryl-tRNA ligase
Synonyms
Evidence for Translation
Charge (pH 7) -9.93
Kyte-Doolittle Hydrophobicity Value -0.356
Molecular Weight (kDa) 47.2
Isoelectric Point (pI) 5.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6HE1 LIGASE 08/20/18 Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine Pseudomonas aeruginosa 2.22 X-RAY DIFFRACTION 99.8
6HE3 LIGASE 08/20/18 Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)cytidine Pseudomonas aeruginosa 2.16 X-RAY DIFFRACTION 99.8
6HDZ LIGASE 08/20/18 Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-Sulfamoyl)uridine Pseudomonas aeruginosa 2.06 X-RAY DIFFRACTION 99.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 651 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002939 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: G655_11940
Search term: seryl-tRNA ligase

Human Homologs

Ensembl 110, assembly GRCh38.p14
seryl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:10537]
E-value: 1.5e-52
Percent Identity: 32.2

References

No references are associated with this feature.