Pseudomonas aeruginosa B136-33, G655_18065

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa B136-33
GCF_000359505.1|latest
Locus Tag
G655_18065
Name
Replicon chromosome
Genomic location 3981788 - 3982459 (- strand)

Cross-References

RefSeq YP_007710453.1
GI 478479802
Entrez 15136518
NCBI Locus Tag G655_18065

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator LasR
Synonyms
Evidence for Translation
Charge (pH 7) -0.69
Kyte-Doolittle Hydrophobicity Value -0.033
Molecular Weight (kDa) 24.9
Isoelectric Point (pI) 6.78

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6MWH TRANSCRIPTION 10/29/18 LasR LBD:BB0020 complex Pseudomonas aeruginosa (strain UCBPP-PA14) 2.2 X-RAY DIFFRACTION 99.6
3IX3 TRANSCRIPTION 09/03/09 LasR-OC12 HSL complex Pseudomonas aeruginosa 1.4 X-RAY DIFFRACTION 99.4
3IX4 TRANSCRIPTION 09/03/09 LasR-TP1 complex Pseudomonas aeruginosa 1.8 X-RAY DIFFRACTION 99.4
6MWZ TRANSCRIPTION 10/30/18 LasR LBD T75V/Y93F/A127W:BB0126 Pseudomonas aeruginosa (strain UCBPP-PA14); Pseudomonas aeruginosa UCBPP-PA14 1.657 X-RAY DIFFRACTION 98.2
6V7X DNA BINDING PROTEIN/Viral protein 12/09/19 Structure of a phage-encoded quorum sensing anti-activator, Aqs1 bound to LasR Pseudomonas aeruginosa (strain UCBPP-PA14); Pseudomonas virus DMS3 2.9 X-RAY DIFFRACTION 99.6
2UV0 TRANSCRIPTION 03/08/07 Structure of the P. aeruginosa LasR ligand-binding domain bound to its autoinducer PSEUDOMONAS AERUGINOSA 1.8 X-RAY DIFFRACTION 99.4
6MVN TRANSCRIPTION 10/26/18 LasR LBD L130F:3OC10HSL complex Pseudomonas aeruginosa (strain UCBPP-PA14) 2.2 X-RAY DIFFRACTION 99.1
6V7W DNA BINDING PROTEIN/Viral protein 12/09/19 Crystal structure of LasR-Aqs1 complex from Pseudomonas aeruginosa Pseudomonas aeruginosa (strain UCBPP-PA14); Pseudomonas virus DMS3 3 X-RAY DIFFRACTION 99.6
3JPU TRANSCRIPTION 09/04/09 LasR-TP4 complex Pseudomonas aeruginosa 2.3 X-RAY DIFFRACTION 99.4
6MWL TRANSCRIPTION 10/29/18 LasR LBD:mBTL complex Pseudomonas aeruginosa (strain UCBPP-PA14) 1.5 X-RAY DIFFRACTION 99.6
3IX8 TRANSCRIPTION 09/03/09 LasR-TP3 complex Pseudomonas aeruginosa 1.8 X-RAY DIFFRACTION 99.4
6MWW TRANSCRIPTION 10/30/18 LasR LBD:BB0126 complex Pseudomonas aeruginosa (strain UCBPP-PA14) 2.76 X-RAY DIFFRACTION 99.6

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 144 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001096 (1439 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: G655_18065

Human Homologs

References

No references are associated with this feature.