Pseudomonas aeruginosa RP73, M062_02170
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa RP73
GCF_000414035.1|latest |
| Locus Tag |
M062_02170
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 477324 - 478733 (- strand) |
Cross-References
| RefSeq | YP_008130898.1 |
| GI | 514408033 |
| Entrez | 15958177 |
| NCBI Locus Tag | M062_02170 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
adenosylhomocysteinase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -7.34 |
| Kyte-Doolittle Hydrophobicity Value | -0.189 |
| Molecular Weight (kDa) | 51.4 |
| Isoelectric Point (pI) | 5.96 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 6F3O | HYDROLASE | 11/28/17 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa complexed with adenine, K+ and Zn2+ cations | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 1.75 | X-RAY DIFFRACTION | 100.0 |
| 6F3M | HYDROLASE | 11/28/17 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa complexed with adenosine, K+ and Zn2+ cations | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 1.6 | X-RAY DIFFRACTION | 100.0 |
| 6F3N | HYDROLASE | 11/28/17 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa cocrystallized with SAH in the presence of K+ and Zn2+ cations | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 1.85 | X-RAY DIFFRACTION | 100.0 |
| 6F3P | HYDROLASE | 11/28/17 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa in complex with 3'-deoxyadenosine and K+ cation | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 1.35 | X-RAY DIFFRACTION | 100.0 |
| 6F3Q | HYDROLASE | 11/28/17 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa in complex with adenine and Rb+ cation | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 1.45 | X-RAY DIFFRACTION | 100.0 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 500 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000423 (554 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: M062_02170
Search term: adenosylhomocysteinase
|
Human Homologs
|
Ensembl
107, assembly
GRCh38.p13
|
adenosylhomocysteinase [Source:HGNC Symbol;Acc:HGNC:343]
E-value:
1.3e-134
Percent Identity:
56.2
|
References
No references are associated with this feature.