Strain |
Pseudomonas aeruginosa RP73
GCF_000414035.1|latest |
Locus Tag |
M062_18930
|
Name |
|
Replicon | chromosome |
Genomic location | 4063199 - 4063837 (+ strand) |
RefSeq | YP_008134195.1 |
GI | 514410772 |
Entrez | 15961525 |
NCBI Locus Tag | M062_18930 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
TetR family transcriptional regulator
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -1.46 |
Kyte-Doolittle Hydrophobicity Value | -0.399 |
Molecular Weight (kDa) | 24.5 |
Isoelectric Point (pI) | 6.63 |
Individual Mappings | |
Additional evidence for subcellular localization |
Identified using the Resistance Gene Identifier (RGI)
Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
nalD | NalD is a repressor of MexAB-OprM. Mutations lead to multidrug resistance and MexAB-OprM overexpression. [PMID:15855496] | ARO:3000819 | protein overexpression model | Strict | 426.8 | 99.53 | 3.2.5 |
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
5DAJ | TRANSCRIPTION REGULATOR | 08/20/15 | Crystal structure of NalD, the secondary repressor of MexAB-OprM multidrug efflux pump in Pseudomonas aeruginosa | Pseudomonas aeruginosa PAO1 | 2.65 | X-RAY DIFFRACTION | 99.5 |
5H9T | TRANSCRIPTION REGULATOR | 12/29/15 | Crystal structure of native NalD at resolution of 2.9, the secondary repressor of MexAB-OprM multidrug efflux pump in Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) | 2.89 | X-RAY DIFFRACTION | 99.5 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 331 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002095 (523 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: M062_18930
Search term: TetR family transcriptional regulator
|