Pseudomonas entomophila L48, PSEEN4359 (ttgR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas entomophila L48
GCF_000026105.1|latest
Locus Tag
PSEEN4359
Name
ttgR
Replicon chromosome
Genomic location 4649257 - 4649889 (- strand)

Cross-References

RefSeq YP_609828.1
GI 104783330
Entrez 4085920

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator TtgR
Synonyms
Evidence for Translation
Charge (pH 7) -6.43
Kyte-Doolittle Hydrophobicity Value -0.229
Molecular Weight (kDa) 23948.1
Isoelectric Point (pI) 5.38

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7K1C TRANSCRIPTION 09/07/20 TtgR in complex with resveratrol Pseudomonas putida 1.9 X-RAY DIFFRACTION 92.4
2UXU TRANSCRIPTION 03/29/07 TtgR in complex with Naringenin PSEUDOMONAS PUTIDA 2.3 X-RAY DIFFRACTION 92.4
2UXH TRANSCRIPTION 03/28/07 TtgR in complex with Quercetin PSEUDOMONAS PUTIDA 2.4 X-RAY DIFFRACTION 92.4
2XDN TRANSCRIPTION 05/04/10 Transcription factor TtgR H67A mutant PSEUDOMONAS PUTIDA 2.2 X-RAY DIFFRACTION 91.9
2UXP TRANSCRIPTION 03/29/07 TtgR in complex Chloramphenicol PSEUDOMONAS PUTIDA 2.7 X-RAY DIFFRACTION 92.4
7K1A TRANSCRIPTION 09/07/20 TtgR quadruple mutant (C137I I141W M167L F168Y) Pseudomonas putida 1.75 X-RAY DIFFRACTION 91.4
7KD8 TRANSCRIPTION 10/08/20 TtgR C137I I141W M167L F168Y mutant in complex with resveratrol Pseudomonas putida 1.71 X-RAY DIFFRACTION 91.4
2UXO TRANSCRIPTION 03/28/07 TtgR in complex with Tetracycline PSEUDOMONAS PUTIDA 2.7 X-RAY DIFFRACTION 92.4
2UXI TRANSCRIPTION 03/28/07 Phloretin in complex with TtgR PSEUDOMONAS PUTIDA 2.5 X-RAY DIFFRACTION 92.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 338 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002095 (523 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSEEN4359
Search term: ttgR

Human Homologs

References

No references are associated with this feature.