Pseudomonas mendocina NK-01, MDS_4545

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas mendocina NK-01
GCF_000204295.1|latest
Locus Tag
MDS_4545
Name
Replicon chromosome
Genomic location 4979482 - 4980276 (- strand)

Cross-References

RefSeq YP_004382328.1
GI 330505459
Entrez 10459327
INSDC AEB60576.1
NCBI Locus Tag MDS_4545
UniParc UPI000206E527
UniProtKB Acc F4DP49
UniProtKB ID F4DP49_PSEMN
UniRef100 UniRef100_F4DP49
UniRef50 UniRef50_P11044
UniRef90 UniRef90_A4VGL9

Product

Feature Type CDS
Coding Frame 1
Product Name
thymidylate synthase
Synonyms
Evidence for Translation
Charge (pH 7) -4.99
Kyte-Doolittle Hydrophobicity Value -0.184
Molecular Weight (kDa) 30.2
Isoelectric Point (pI) 6.03

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 402 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000334 (395 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: MDS_4545

Human Homologs

Ensembl 110, assembly GRCh38.p14
thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441]
E-value: 1.8e-80
Percent Identity: 50.7

References

No references are associated with this feature.