Pseudomonas sp. UW4, PputUW4_03520 (topA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas sp. UW4
GCF_000316175.1|latest |
| Locus Tag |
PputUW4_03520
|
| Name |
topA
|
| Replicon | chromosome |
| Genomic location | 4087242 - 4089869 (- strand) |
Cross-References
| RefSeq | YP_007030518.1 |
| GI | 426410419 |
| EC Number | 5.99.1.2 |
| Entrez | 14054510 |
| NCBI Locus Tag | PputUW4_03520 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
DNA topoisomerase I
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 8.49 |
| Kyte-Doolittle Hydrophobicity Value | -0.545 |
| Molecular Weight (kDa) | 97312.1 |
| Isoelectric Point (pI) | 8.23 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 665 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG002571 (536 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PputUW4_03520
Search term: topA
Search term: DNA topoisomerase I
|
Human Homologs
References
No references are associated with this feature.