Pseudomonas protegens Pf-5, PFL_3271 (acrB)

Gene Feature Overview

Strain	Pseudomonas protegens Pf-5 GCF_000012265.1|latest
Locus Tag	PFL_3271
Name	acrB
Replicon	chromosome
Genomic location	3776576 - 3779674 (+ strand)

Cross-References

RefSeq	YP_260376.1
GI	70730635
Entrez	3477813
INSDC	AAY92540.1
NCBI Locus Tag	PFL_3271
UniParc	UPI000054D7CD
UniProtKB Acc	Q4KBK7
UniProtKB ID	Q4KBK7_PSEF5
UniRef100	UniRef100_Q4KBK7
UniRef50	UniRef50_P52002
UniRef90	UniRef90_Q4KBK7

Product

Feature Type	CDS
Coding Frame	1
Product Name	acriflavine resistance protein B
Synonyms
Evidence for Translation
Charge (pH 7)	-9.34
Kyte-Doolittle Hydrophobicity Value	0.360
Molecular Weight (kDa)	110304.7
Isoelectric Point (pI)	5.28

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name	Definition	Accession	Model Type (?)	SNP	Cutoff	Bit Score	Percent Identity	CARD Version
adeF	AdeF is the membrane fusion protein of the multidrug efflux complex AdeFGH. [PMID:20696879]	ARO:3000777	protein homolog model		Strict	782.3	44.02	3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 487 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000417 (2093 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PFL_3271 Search term: acrB Search term: acriflavine resistance protein B

Human Homologs

References