Pseudomonas protegens Pf-5, PFL_4797 (pyk_2)

Gene Feature Overview

Strain	Pseudomonas protegens Pf-5 GCF_000012265.1|latest
Locus Tag	PFL_4797
Name	pyk_2
Replicon	chromosome
Genomic location	5537332 - 5538783 (+ strand)

Cross-References

RefSeq	YP_261878.1
GI	70732122
EC Number	2.7.1.40
Entrez	3479208
INSDC	AAY94027.1
NCBI Locus Tag	PFL_4797
UniParc	UPI000054DDA1
UniProtKB Acc	Q4K7A5
UniProtKB ID	Q4K7A5_PSEF5
UniRef100	UniRef100_Q4K7A5
UniRef50	UniRef50_Q4K7A5
UniRef90	UniRef90_Q4K7A5

Product

Feature Type	CDS
Coding Frame	1
Product Name	pyruvate kinase
Synonyms
Evidence for Translation
Charge (pH 7)	-3.73
Kyte-Doolittle Hydrophobicity Value	-0.083
Molecular Weight (kDa)	52.0
Isoelectric Point (pI)	6.52

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 614 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003926 (537 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PFL_4797 Search term: pyk_2 Search term: pyruvate kinase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000334983 pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] E-value: 1.8e-67 Percent Identity: 36.4
Ensembl 110, assembly GRCh38.p14	ENSP00000513903 pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] E-value: 1.8e-67 Percent Identity: 36.4

References