Pseudomonas denitrificans ATCC 13867, H681_00755

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas denitrificans ATCC 13867
GCF_000349845.1|latest
Locus Tag
H681_00755
Name
Replicon chromosome
Genomic location 164885 - 166381 (+ strand)

Cross-References

RefSeq YP_007655573.1
GI 472323327
Entrez 14994291
INSDC AGI22033.1
NCBI Locus Tag H681_00755
UniParc UPI0002C4F734
UniProtKB Acc M4WPU3
UniProtKB ID M4WPU3_PSEDE
UniRef100 UniRef100_M4WPU3
UniRef50 UniRef50_Q9I702
UniRef90 UniRef90_Q9I702

Product

Feature Type CDS
Coding Frame 1
Product Name
methylmalonate-semialdehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -9.12
Kyte-Doolittle Hydrophobicity Value -0.023
Molecular Weight (kDa) 53593.9
Isoelectric Point (pI) 5.36

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5TJR OXIDOREDUCTASE 10/05/16 X-ray Crystal structure of a methylmalonate semialdehyde dehydrogenase from Pseudomonas sp. AAC Pseudomonas sp. AAC 2.95 X-RAY DIFFRACTION 94.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 596 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000128 (531 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: H681_00755

Human Homologs

Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 6 family member A1 [Source:HGNC Symbol;Acc:HGNC:7179]
E-value: 4.6e-130
Percent Identity: 45.4

References

No references are associated with this feature.