Pseudomonas denitrificans ATCC 13867, H681_22785

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in GBrowse

Gene Feature Overview

Strain Pseudomonas denitrificans ATCC 13867
GCF_000349845.1|latest
Locus Tag
H681_22785
Name
Replicon chromosome
Genomic location 5107474 - 5108883 (+ strand)

Cross-References

RefSeq YP_007659964.1
GI 472327718
EC Number 3.3.1.1
Entrez 14998682
NCBI Locus Tag H681_22785

Product

Feature Type CDS
Coding Frame 1
Product Name
S-adenosyl-L-homocysteine hydrolase
Synonyms
Evidence for Translation
Charge (pH 7) -8.85
Kyte-Doolittle Hydrophobicity Value -0.132
Molecular Weight (kDa) 51193.3
Isoelectric Point (pI) 5.49

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6F3N HYDROLASE 11/28/17 Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa cocrystallized with SAH in the presence of K+ and Zn2+ cations PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.85 X-RAY DIFFRACTION 93.2
6F3O HYDROLASE 11/28/17 Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa complexed with adenine, K+ and Zn2+ cations PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.75 X-RAY DIFFRACTION 93.2
6F3P HYDROLASE 11/28/17 Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa in complex with 3'-deoxyadenosine and K+ cation PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.35 X-RAY DIFFRACTION 93.2
6F3Q HYDROLASE 11/28/17 Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa in complex with adenine and Rb+ cation PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.45 X-RAY DIFFRACTION 93.2
6F3M HYDROLASE 11/28/17 Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa complexed with adenosine, K+ and Zn2+ cations PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.6 X-RAY DIFFRACTION 93.1

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 500 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000423 (554 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: H681_22785

Human Homologs

Ensembl 97, assembly GRCh38.p12
adenosylhomocysteinase [Source:HGNC Symbol;Acc:HGNC:343]
E-value: 4.4e-131
Percent Identity: 54.7

References

No references are associated with this feature.