Pseudomonas aeruginosa 2192, PA2G_02300

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa 2192
GCF_000152545.1|latest
Locus Tag
PA2G_02300
Name
Replicon chromosome
Genomic location 2582939 - 2583898 (+ strand)

Cross-References

RefSeq ZP_04934921.1
GI 254241599
NCBI Locus Tag PA2G_02300
UniProtKB Acc A3LBX2
UniProtKB ID A3LBX2_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
putative hydrolase
Synonyms
Evidence for Translation
Charge (pH 7) -3.21
Kyte-Doolittle Hydrophobicity Value -0.149
Molecular Weight (kDa) 35.8
Isoelectric Point (pI) 6.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4EUS HYDROLASE 04/25/12 Crystal structure of the CFTR inhibitory factor Cif bound to 1,2-hexanediol Pseudomonas aeruginosa 1.65 X-RAY DIFFRACTION 100.0
5HK9 HYDROLASE/HYDROLASE INHIBITOR 01/13/16 Crystal structure of the CFTR inhibitory factor Cif bound to a urea inhibitor Pseudomonas aeruginosa (strain UCBPP-PA14) 1.8 X-RAY DIFFRACTION 100.0
5HKA Hydrolase/Hydrolase inhibitor 01/13/16 Crystal structure of the CFTR inhibitory factor Cif bound to an amide inhibitor Pseudomonas aeruginosa (strain UCBPP-PA14) 2.05 X-RAY DIFFRACTION 100.0
5HKB Hydrolase/Hydrolase inhibitor 01/13/16 Crystal structure of the CFTR inhibitory factor Cif bound to the inhibitor KB2115 Pseudomonas aeruginosa UCBPP-PA14 1.65 X-RAY DIFFRACTION 100.0
5TNM HYDROLASE 10/14/16 Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted (R)-1,2-Epoxyoctane hydrolysis intermediate Pseudomonas aeruginosa (strain UCBPP-PA14) 1.7 X-RAY DIFFRACTION 99.7
3KD2 HYDROLASE 10/22/09 Crystal structure of the CFTR inhibitory factor Cif Pseudomonas aeruginosa UCBPP-PA14 1.8 X-RAY DIFFRACTION 100.0
4YX9 Hydrolase/Hydrolase inhibitor 03/22/15 Crystal structure of the CFTR inhibitory factor Cif bound to tiratricol Pseudomonas aeruginosa (strain UCBPP-PA14) 1.75 X-RAY DIFFRACTION 100.0

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000798 (2691 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2G_02300

Human Homologs

Ensembl 110, assembly GRCh38.p14
mesoderm specific transcript [Source:HGNC Symbol;Acc:HGNC:7028]
E-value: 8.5e-05
Percent Identity: 32.5
Ensembl 110, assembly GRCh38.p14
mesoderm specific transcript [Source:HGNC Symbol;Acc:HGNC:7028]
E-value: 8.5e-05
Percent Identity: 32.5
Ensembl 110, assembly GRCh38.p14
mesoderm specific transcript [Source:HGNC Symbol;Acc:HGNC:7028]
E-value: 8.5e-05
Percent Identity: 32.5
Ensembl 110, assembly GRCh38.p14
mesoderm specific transcript [Source:HGNC Symbol;Acc:HGNC:7028]
E-value: 8.5e-05
Percent Identity: 32.5
Ensembl 110, assembly GRCh38.p14
mesoderm specific transcript [Source:HGNC Symbol;Acc:HGNC:7028]
E-value: 8.5e-05
Percent Identity: 32.5
Ensembl 110, assembly GRCh38.p14
mesoderm specific transcript [Source:HGNC Symbol;Acc:HGNC:7028]
E-value: 8.5e-05
Percent Identity: 32.5
Ensembl 110, assembly GRCh38.p14
mesoderm specific transcript [Source:HGNC Symbol;Acc:HGNC:7028]
E-value: 8.5e-05
Percent Identity: 32.5
Ensembl 110, assembly GRCh38.p14
mesoderm specific transcript [Source:HGNC Symbol;Acc:HGNC:7028]
E-value: 8.5e-05
Percent Identity: 32.5
Ensembl 110, assembly GRCh38.p14
mesoderm specific transcript [Source:HGNC Symbol;Acc:HGNC:7028]
E-value: 8.5e-05
Percent Identity: 32.5
Ensembl 110, assembly GRCh38.p14
mesoderm specific transcript [Source:HGNC Symbol;Acc:HGNC:7028]
E-value: 8.5e-05
Percent Identity: 32.5
Ensembl 110, assembly GRCh38.p14
mesoderm specific transcript [Source:HGNC Symbol;Acc:HGNC:7028]
E-value: 8.5e-05
Percent Identity: 32.5

References

No references are associated with this feature.