Pseudomonas aeruginosa LESB58, PALES_16541 (hasAp)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa LESB58
GCF_000026645.1|latest
Locus Tag
PALES_16541
Name
hasAp
Replicon chromosome
Genomic location 1778427 - 1779044 (+ strand)

Cross-References

RefSeq YP_002439258
GI 218890394
Entrez 7180108

Product

Feature Type CDS
Coding Frame 1
Product Name
heme acquisition protein HasAp
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -12.57
Kyte-Doolittle Hydrophobicity Value 0.065
Molecular Weight (kDa) 20.9
Isoelectric Point (pI) 4.13

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7EMR TRANSPORT PROTEIN 04/14/21 Crystal Structure of HasAp Capturing Cobalt Tetraphenylporphyrin Pseudomonas aeruginosa str. PAO1 1.55 X-RAY DIFFRACTION 100.0
6URB METAL BINDING PROTEIN 10/23/19 Pseudomonas aeruginosa HasA mutant - H32A Pseudomonas aeruginosa 2.096 X-RAY DIFFRACTION 99.0
6U87 METAL BINDING PROTEIN 09/04/19 Pseudomonas aeruginosa HasA mutant - Y75H Pseudomonas aeruginosa 1.3 X-RAY DIFFRACTION 99.0
6JLG TRANSPORT PROTEIN 03/05/19 Crystal Structure of HasAp with Co-9,10,19,20-Tetraphenylporphycene Pseudomonas aeruginosa 2.5 X-RAY DIFFRACTION 100.0
5XIE TRANSPORT PROTEIN 04/26/17 Crystal Structure of HasAp with 5-ethynyl-10,20-diphenylporphyrin Pseudomonas aeruginosa str. PAO1 2.05 X-RAY DIFFRACTION 100.0
7VM1 TRANSPORT PROTEIN 10/06/21 Crystal Structure of HasAp Capturing Iron Tetra(4-pyridyl)porphyrin Pseudomonas aeruginosa str. PAO1 2 X-RAY DIFFRACTION 100.0
5XKB TRANSPORT PROTEIN 05/06/17 Crystal Structure of HasAp with Fe-5,15-bisethynyl-10,20-diphenylporphyrin Pseudomonas aeruginosa str. PAO1 1.9 X-RAY DIFFRACTION 100.0
7VF7 METAL TRANSPORT 09/10/21 Crystal Structure of HasAp with Co-octaethylporphyrin Pseudomonas aeruginosa str. PAO1 1.35 X-RAY DIFFRACTION 100.0
7VF8 METAL TRANSPORT 09/10/21 Crystal Structure of HasAp with Co-5-octaethyloxaporphyrinium cation Pseudomonas aeruginosa str. PAO1 1.35 X-RAY DIFFRACTION 100.0
7EMO TRANSPORT PROTEIN 04/14/21 Crystal Structure of HasAp Capturing Iron Tetraphenylporphyrin Pseudomonas aeruginosa str. PAO1 1.5 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 6 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002223 (338 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PALES_16541
Search term: hasAp

Human Homologs

References

No references are associated with this feature.