Pseudomonas aeruginosa 2192, PA2G_05647

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa 2192
GCF_000152545.1|latest
Locus Tag
PA2G_05647
Name
Replicon chromosome
Genomic location 6291959 - 6293305 (+ strand)

Cross-References

RefSeq ZP_04938097.1
GI 254244775
NCBI Locus Tag PA2G_05647
UniProtKB Acc A3LL85
UniProtKB ID A3LL85_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -6.27
Kyte-Doolittle Hydrophobicity Value 0.125
Molecular Weight (kDa) 48.1
Isoelectric Point (pI) 5.70

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7U35 LIGASE 02/25/22 Crystal Structure of UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from Pseudomonas aeruginosa PAO1 in complex with ADP Pseudomonas aeruginosa PAO1 1.95 X-RAY DIFFRACTION 100.0
8DP2 LIGASE 07/14/22 Crystal Structure of UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from Pseudomonas aeruginosa PAO1 in complex with UMA (Uridine-5'-diphosphate-N-acetylmuramoyl-L-Alanine) Pseudomonas aeruginosa PAO1 1.6 X-RAY DIFFRACTION 100.0
7SY9 LIGASE 11/24/21 Crystal Structure of UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.75 X-RAY DIFFRACTION 100.0

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004004 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2G_05647

Human Homologs

References

No references are associated with this feature.