Pseudomonas aeruginosa 2192, PA2G_05733

Gene Feature Overview

Strain	Pseudomonas aeruginosa 2192 GCF_000152545.1|latest
Locus Tag	PA2G_05733
Name
Replicon	chromosome
Genomic location	6382456 - 6383907 (- strand)

Cross-References

RefSeq	ZP_04938183.1
GI	254244861
NCBI Locus Tag	PA2G_05733
UniProtKB Acc	A3LLH1
UniProtKB ID	A3LLH1_PSEAE

Product

Feature Type	CDS
Coding Frame	1
Product Name	pyruvate kinase
Synonyms
Evidence for Translation
Charge (pH 7)	-2.24
Kyte-Doolittle Hydrophobicity Value	-0.092
Molecular Weight (kDa)	52.3
Isoelectric Point (pI)	6.66

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
6QXL	TRANSFERASE	03/07/19	Crystal Structure of Pyruvate Kinase II (PykA) from Pseudomonas aeruginosa in complex with sodium malonate, magnesium and glucose-6-phosphate	Pseudomonas aeruginosa	2.43	X-RAY DIFFRACTION	100.0

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003926 (537 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA2G_05733 Search term: pyruvate kinase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000455736 pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] E-value: 3.1e-67 Percent Identity: 36.7
Ensembl 110, assembly GRCh38.p14	ENSP00000456970 pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] E-value: 3.1e-67 Percent Identity: 36.7
Ensembl 110, assembly GRCh38.p14	ENSP00000320171 pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] E-value: 3.1e-67 Percent Identity: 36.7
Ensembl 110, assembly GRCh38.p14	ENSP00000455901 pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] E-value: 3.1e-67 Percent Identity: 36.7

References