Pseudomonas aeruginosa 2192, PA2G_05934

Gene Feature Overview

Strain	Pseudomonas aeruginosa 2192 GCF_000152545.1|latest
Locus Tag	PA2G_05934
Name
Replicon	chromosome
Genomic location	6630221 - 6631117 (- strand)

Cross-References

RefSeq	ZP_04938371.1
GI	254245049
NCBI Locus Tag	PA2G_05934
UniProtKB Acc	A3LM09
UniProtKB ID	A3LM09_PSEAE

Product

Feature Type	CDS
Coding Frame	1
Product Name	2-methylisocitrate lyase
Synonyms
Evidence for Translation
Charge (pH 7)	-5.92
Kyte-Doolittle Hydrophobicity Value	0.032
Molecular Weight (kDa)	32.1
Isoelectric Point (pI)	5.20

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
6T5M	LYASE	10/16/19	Crystal structure of 2-methylisocitrate lyase (PrpB) from Pseudomonas aeruginosa in complex with Mg(II)-pyruvate.	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	1.76	X-RAY DIFFRACTION	100.0
6T4V	LYASE	10/15/19	Crystal structure of 2-methylisocitrate lyase (PrpB) from Pseudomonas aeruginosa in apo form.	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	1.807	X-RAY DIFFRACTION	100.0

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000769 (537 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA2G_05934 Search term: 2-methylisocitrate lyase

Human Homologs

References